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An anonymous reader quotes a report from Reuters: AbbVie will buy an experimental depression drug from partner Gilgamesh Pharmaceuticals for up to $1.2 billion, the companies said on Monday, seeking to access a fast-growing market for psychedelic-based treatments. The deal is the latest in the more than $20 billion AbbVie has spent on acquisitions since 2023 for drugs that can drive growth as its flagship rheumatoid arthritis treatment, Humira, lost patent protection. The companies had signed a partnership last year to develop therapies for psychiatric disorders, with privately held Gilgamesh set to receive up to $1.95 billion in option fees and milestone payments. The deals with Gilgamesh, which is also developing treatments for anxiety and post-traumatic stress disorder, also launch AbbVie into the race to develop psychedelic compounds for psychiatric conditions -- a potential $50 billion market, according to Cantor Fitzgerald analyst Josh Schimmer. The deal, which includes an upfront payment and development milestones, could also bolster AbbVie's neurological conditions portfolio after its experimental schizophrenia drug, which it gained access to through an $8.7 billion purchase of Cerevel Therapeutics, failed in two mid-stage studies last year. Gilgamesh's lead candidate for depression, bretisilocin, activates the 5-HT2A serotonin receptor -- also targeted by classic psychedelics such as psilocybin, found in magic mushrooms, and LSD. The companies said bretisilocin has been shown to exert a shorter duration of psychoactive experience while retaining an extended therapeutic benefit in early and mid-stage studies. AbbVie will advance the drug into late-stage studies. "Large Pharma has been less active exploring psychedelic compounds due to potential regulatory concerns ... making today's deal more significant," said BMO Capital Markets analyst Evan Seigerman.

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Amazon is facing a proposed class action lawsuit alleging it misleads customers by advertising digital movies and TV shows as "purchases," when in reality buyers only receive revocable licenses that can disappear if Amazon loses distribution rights. From the Hollywood Reporter: On Friday, a proposed class action was filed in Washington federal court against Amazon over a "bait and switch" in which the company allegedly misleads consumers into believing they've purchased content when they're only getting a license to watch, which can be revoked at any time. [...] The lawsuit accuses Amazon, which didn't respond to a request for comment, of misrepresenting the nature of movie and TV transactions during the purchase process. On its website and platform, the company tells consumers they can "buy" a movie. But hidden in a footnote on the confirmation page is fine print that says, "You receive a license to the video and you agree to our terms," the complaint says. The issue is already before a court. In a 2020 lawsuit alleging unfair competition and false advertising over the practice, Amazon maintained that its use of the word "buy" for digital content isn't deceptive because consumers understand their purchases are subject to licenses. Quoting Webster's Dictionary, it said that the term means "rights to the use or services of payment" rather than perpetual ownership and that its disclosures properly warn people that they may lose access. The court ultimately rebuffed Amazon's bid to dismiss the lawsuit outside of a claim alleging a violation of Washington's unjust enrichment law.

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Shadow stacks are a control-flow-integrity feature designed to defend against exploits that manipulate a thread's call stack. The kernel first gained support for hardware-implemented shadow stacks, for the x86 architecture, in the 6.6 release; 64-bit Arm support followed in 6.13. This feature does not give user space much control over the allocation of shadow stacks for new threads, though; a patch series from Mark Brown may, after many attempts, finally be about to change that situation.

Security updates have been issued by Debian (ffmpeg, firebird3.0, and luajit), Fedora (chromium, python3-docs, and python3.13), Oracle (aide, firefox, glibc, libxml2, and tomcat), Red Hat (aide, git, kernel, kernel-rt, libarchive, pam, python-cryptography, python3, python3.12, and webkit2gtk3), SUSE (cmake3, ffmpeg-4, kernel, kubernetes1.18, libqt4, minikube, net-tools, pam, postgresql16, proftpd, python-urllib3, python311, python312, python36, tomcat10, tomcat11, and webkit2gtk3), and Ubuntu (nginx).

Russia's new Soyuz-5 rocket is set for a December debut as Moscow seeks to end reliance on Ukrainian technology and replace its aging Proton-M fleet. Ars Technica reports: According to the report, translated for Ars by Rob Mitchell, the debut launch of Soyuz-5 will mark the first of several demonstration flights, with full operational service not expected to begin until 2028. It will launch from the Baikonur spaceport in Kazakhstan. From an innovation standpoint, the Soyuz-5 vehicle does not stand out. It has been a decade in the making and is fully expendable, unlike a lot of newer medium-lift rockets coming online in the next several years. However, for Russia, this is an important advancement because it seeks to break some of the country's dependency on Ukraine for launch technology.

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Two of Japan's largest media groups are suing AI search engine Perplexity over alleged copyright infringement, joining a growing list of news publishers taking legal action against AI companies using their content. FT: Japanese media group Nikkei, which owns the Financial Times, and the Asahi Shimbun newspaper said in statements on Tuesday that they had jointly filed a lawsuit in Tokyo. The groups join a number of Western media companies taking legal action against Perplexity, which provides answers to questions with sources and citations, using large language models (LLMs) from platforms such as OpenAI and Anthropic. The Japanese news providers claim Perplexity has, without permission, "copied and stored article content from the servers of Nikkei and Asahi" and ignored a "technical measure" designed to prevent this from happening. They claim that Perplexity's answers have given incorrect information attributed to the newspapers' articles, which "severely damages the credibility of newspaper companies."

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Google has announced a new set of restrictions on the ability of users to install apps on their own devices:

Starting next year, Android will require all apps to be registered by verified developers in order to be installed by users on certified Android devices. This creates crucial accountability, making it much harder for malicious actors to quickly distribute another harmful app after we take the first one down. Think of it like an ID check at the airport, which confirms a traveler's identity but is separate from the security screening of their bags; we will be confirming who the developer is, not reviewing the content of their app or where it came from.

An anonymous reader quotes a report from Ars Technica: Greenhouse gas reduction is no longer a priority for the US government, but if you're looking for a new vehicle and want to buy something with the lowest life cycle carbon emissions, you're best off looking for a compact with a small battery. That's one of the findings from a group at the University of Michigan of a comprehensive study that calculates the overall cradle-to-grave carbon impact for different types of vehicles, including factors like powertrain options, location (within the country), and use patterns. Even better, they built a tool you can use yourself. The study, published in Environmental Science and Technology, compares internal combustion engine powertrains with hybrid, 35- and 50-mile range plug-in hybrids, and 200-mile, 300-mile, and 400-mile battery electric powertrains across compact and midsize sedans, small and midsize SUVs, and pickup trucks, using a life cycle assessment model developed by Argonne National Laboratory and data of model year 2025 vehicles from the Environmental Protection Agency. If you expected that a gas-powered pickup truck would have the biggest carbon footprint, you'd be right. With a driving profile of 43 percent city driving and the rest highways (no cargo), a pickup will emit about 486 g CO2e per mile. Compared to that, a compact electric sedan with a 200-mile battery has just 17 percent of the life cycle emissions and is responsible for just 81 g CO2e per mile. A short-range electric pickup -- maybe that Slate that so many are salivating over -- is nearly as good, with a footprint that's only 25 percent the size of the gas pickup truck. On the other hand, hybrid powertrains (the kind that don't plug in) only reduce life cycle carbon compared to internal combustion alone by a modest amount -- between 11 and 13 percent, depending on the vehicle class. Plug-in hybrids with 35 miles of range can reduce emissions compared to plain combustion by 53-56 percent; with 50-mile batteries the reduction is 56-60 percent, assuming the PHEVs were driven in electric mode for 58 percent and 69 percent of the time, respectively. When it comes to BEVs, the smallest battery pack always has the least environmental impact. BEV powertrains with 400 miles of range have lifecycle emissions that are 67-69 percent lower than an ICE powertrain in the same vehicle. For 300-mile BEVs, this is an 81-83 percent reduction. A 200-mile BEV can be expected to contribute just 25-26 percent as much CO2e as an equivalent gas-burning vehicle would. That's not because EVs with big batteries are inefficient -- far from it -- but because making a battery for an EV is a very energy-intensive process. Most emissions from internal combustion engine (92 percent) and hybrid (89 percent) vehicles come from their use on the roads. But this changes once you start adding significant kWh-worth of battery. For PHEVs, the use phase is more like 73-80 percent, and for BEVs, it's just 48-60 percent, depending on the size of the batteries. The researchers also modeled different driving behaviors, including the use cases of someone who uses their vehicle just to commute and run errands; the "occasional road-tripper," most of whose needs are met by a small battery; and a contractor or someone else who has to drive a lot for work, with varying amounts of cargo onboard. As we've known for some time, where you get your energy from affects how clean your EV will be, and switching from gasoline to an EV has more of an impact in Seattle (which relies on hydropower) versus Cincinnati (where the electricity comes from burning coal), for both PHEVs and BEVs.

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Farmers Insurance disclosed a breach affecting 1.1 million customers after attackers exploited Salesforce in a widespread campaign involving ShinyHunters and allied groups. According to BleepingComputer, the hackers stole personal data such as names, birth dates, driver's license numbers, and partial Social Security numbers. From the report: The company disclosed the data breach in an advisory on its website, saying that its database at a third-party vendor was breached on May 29, 2025. "On May 30, 2025, one of Farmers' third-party vendors alerted Farmers to suspicious activity involving an unauthorized actor accessing one of the vendor's databases containing Farmers customer information (the "Incident")," reads the data breach notification (PDF) on its website. "The third-party vendor had monitoring tools in place, which allowed the vendor to quickly detect the activity and take appropriate containment measures, including blocking the unauthorized actor. After learning of the activity, Farmers immediately launched a comprehensive investigation to determine the nature and scope of the Incident and notified appropriate law enforcement authorities." The company says that its investigation determined that customers' names, addresses, dates of birth, driver's license numbers, and/or last four digits of Social Security numbers were stolen during the breach. Farmers began sending data breach notifications to impacted individuals on August 22, with a sample notification [1, 2] shared with the Maine Attorney General's Office, stating that a combined total of 1,111,386 customers were impacted. While Farmers did not disclose the name of the third-party vendor, BleepingComputer has learned that the data was stolen in the widespread Salesforce data theft attacks that have impacted numerous organizations this year. Further reading: Google Suffers Data Breach in Ongoing Salesforce Data Theft Attacks

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Mark Tyson writes via Tom's Hardware: On this day 34 years ago, an unknown computer science student from Finland announced that a new free operating system project was "starting to get ready." Linus Benedict Torvalds elaborated by explaining that the OS was "just a hobby, [it] won't be big and professional like GNU." Of course, this was the first public outing for the colossal collaborative project that is now known as Linux. Above, you can see Torvalds' first posting regarding Linux to the comp.os.minix newsgroup. The now famously caustic, cantankerous, curmudgeon seemed relatively mild, meek, and malleable in this historic Linux milestone posting. Torvalds asked the Minix community about their thoughts on a free new OS being prepared for Intel 386 and 486 clones. He explained that he'd been brewing the project since April (a few months prior), and asked for direction. Specifically, he sought input about other Minix users' likes and dislikes of that OS, in order to differentiate Linux. The now renowned developer then provided a rough summary of the development so far. Some features of Linux that Torvalds thought were important, or that he was particularly proud of, were then highlighted in the newsgroup posting. For example, the Linux chief mentioned his OS's multithreaded file system, and its absence of any Minix code. However, he humbly admitted the code as it stood was Intel x86 specific, and thus "is not portable." Last but not least, Torvalds let it be known that version 0.01 of this free OS would be out in the coming month (September 1991). It was indeed released on September 17, 1991, but someone else decided on the OS name at the last minute. Apparently, Torvalds didn't want to release his new OS under the name of Linux, as it would be too egotistical, too self-aggrandizing. He preferred Freax, a portmanteau word formed from Free-and-X. However, one of Torvald's colleagues, who was the administrator for the project's FTP server, did not think that 'Freax' was an appealing name for the OS. So this co-worker went ahead and uploaded the OS as 'Linux' on that date in September, without asking Torvalds.

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Struggling small biotech firms are pivoting into cryptocurrencies, rebranding as "crypto treasuries" or stockpiling digital assets like Ether and Litecoin as a last-ditch effort to boost share prices amid stalled funding and weak drug pipelines. Bloomberg reports: Shares of 180 Life Sciences Corp., now doing business as ETHZilla, tripled after the Peter Thiel-backed company said it had accumulated Ether tokens worth over $350 million. Less than two weeks later, the stock's gains have been erased. In July, Sonnet BioTherapeutics Holdings soared 243% in one volatile session on plans to transform into a public crypto treasury while MEI Pharma Inc. initially doubled on plans to sell shares to fund a Litecoin treasury. Such about-faces are a tried-and-true formula for small firms when funds are low and shares are under pressure. For drugmakers it can be a sudden shift to chase after trendy new treatment targets, still other companies rebrand with buzzwords like artificial intelligence to juice returns. Now some biotech executives are using digital coins to pump new life into flagging shares. So far in 2025, at least 10 biotechs have announced a pivot into digital assets. The announcements frequently spark frenzied, but short-lived, spikes in shares. "If they're low on ideas, if they can't find relevance in drug development, they're going to try to justify their existence as management in another way," according to Mike Taylor, lead portfolio manager of the Simplify Health Care ETF. "You have a handful of companies trying to reinvent themselves into some other tangent. And, most, if not all won't work out."

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An anonymous reader quotes a report from Ars Technica: AMD's X3D-series Ryzen chips have become popular with PC gamers because games in particular happen to benefit disproportionately from the chips' extra 64MB of L3 cache memory. But that extra memory occasionally comes with extra headaches. Not long after they were released earlier this year, some early adopters started having problems with their CPUs, ranging from failure to boot to actual physical scorching and burnout -- the problems were particularly common for users of the 9800X3D processor in ASRock motherboards, and one Reddit thread currently records 157 incidents of failure for that CPU model across various ASRock boards. In an interview with the Korean language website Quasar Zone (via Tom's Hardware), AMD executives David McAfee and Travis Kirsch acknowledged the problems and pointed to the most likely culprit: motherboard makers who don't follow AMD's recommended specifications. Some manufacturers have historically shipped their AMD and Intel motherboards with elevated default power settings in the interest of squeezing a bit more performance out of the chips -- but those adjustments can also cause problems in some cases, especially for higher-end CPUs.

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Apple has filed a lawsuit against former Apple Watch staffer Dr. Chen Shi, alleging that he "conspired to steal Apple's trade secrets relating to Apple Watch and to disclose them to his new employers (Oppo)." The company alleges he downloaded 63 sensitive documents, attended technical meetings, and coordinated with Oppo to transfer proprietary information, though Oppo denies wrongdoing. The Verge reports: Ahead of starting his new job at Oppo, the employee, Dr. Chen Shi, attended "dozens" of meetings with technical members on the Apple Watch team to learn about their work and downloaded 63 documents "from a protected Box folder" that he loaded onto a USB drive, according to the lawsuit. Shi allegedly sent a message to Oppo saying that he was working to "collect as much information as possible" before starting his job. And he searched the internet for terms like "how to wipe out macbook" and "Can somebody see if I've opened a file on a shared drive?" from his Apple-issued MacBook before leaving the company. Shi was formerly a sensor system architect at Apple, and the company says he had "a front row seat to Apple's development of its cutting-edge health sensor technology, including highly confidential roadmaps, design and development documents, and specifications for ECG sensor technology." He now heads up a team working on sensing technology at Oppo -- which Apple says it learned because of "messages he left on his Apple-issued work iPhone." In his resignation letter to Apple, Shi said he was leaving "due to personal and family reasons." Via that iPhone, Apple also says it found messages from Oppo demonstrating that it "encouraged, approved, and agreed to Dr. Shi's plan to collect Apple's proprietary information before leaving Apple."

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Nvidia has launched its Jetson AGX Thor robotics chip module, a $3,499 "robot brain" developer kit that starts shipping next month. CNBC reports: After a company uses the developer kit to prototype their robot, Nvidia will sell Thor T5000 modules that can be installed in production-ready robots. If a company needs more than 1,000 Thor chips, Nvidia will charge $2,999 per module. CEO Jensen Huang has said robotics is the company's largest growth opportunity outside of artificial intelligence, which has led to Nvidia's overall sales more than tripling in the past two years. "We do not build robots, we do not build cars, but we enable the whole industry with our infrastructure computers and the associated software," said Deepu Talla, Nvidia's vice president of robotics and edge AI, on a call with reporters Friday. The Jetson Thor chips are based on a Blackwell graphics processor, which is Nvidia's current generation of technology used in its AI chips, as well as its chips for computer games. Nvidia said that its Jetson Thor chips are 7.5 times faster than its previous generation. That allows them to run generative AI models, including large language models and visual models that can interpret the world around them, which is essential for humanoid robots, Nvidia said. The Jetson Thor chips are equipped with 128GB of memory, which is essential for big AI models. [...] The company said its Jetson Thor chips can be used for self-driving cars as well, especially from Chinese brands. Nvidia calls its car chips Drive AGX, and while they are similar to its robotics chips, they run an operating system called Drive OS that's been tuned for automotive purposes.

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An anonymous reader quotes a report from PYMNTS: Artificial intelligence startup Perplexity has announced a new subscription program called Comet Plus that it said gives users access to premium content from trusted publishers and journalists, while providing publishers with a better compensation model. "Comet Plus transforms how publishers are compensated in the AI age," the company said in a Monday blog post. "As users demand a better internet in the age of AI, it's time for a business model to ensure that publishers and journalists benefit from their contributions to a better internet." Comet Plus is included in Perplexity's Pro and Max memberships and is available as a standalone subscription for $5 per month. Perplexity introduced its Comet AI-powered browser in July, saying the tool lets users answer questions and carry out tasks and research from a single interface. Bloomberg reported Monday that Perplexity has allocated $42.5 million for a revenue sharing program that compensates publishers when their content is used by its Comet browser or AI assistant. The program will use funds that come from Comet Plus and will deliver 80% of the revenue to publishers, with Perplexity getting the other 20%, the report said, citing an interview with Perplexity CEO Aravind Srinivas. "AI is helping to create a better internet, but publishers still need to get paid," Srinivas said in the report. "Sowe think this is actually the right solution, and we're happy to make adjustments along the way."

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The Federal Trade Commission is warning major U.S. tech companies against yielding to foreign government demands that weaken data security, compromise encryption, or impose censorship on their platforms. From a report: FTC Chairman Andrew N. Ferguson signed the letter sent to large American companies like Akamai, Alphabet (Google), Amazon, Apple, Cloudflare, Discord, GoDaddy, Meta, Microsoft, Signal, Snap, Slack, and X (Twitter). Ferguson stresses that weakening data security at the request of foreign governments, especially if they don't alert users about it, would constitute a violation of the FTC Act and expose companies to legal consequences. Ferguson's letter specifically cites foreign laws such as the EU's Digital Services Act and the UK's Online Safety and Investigatory Powers Acts. Earlier this year, Apple was forced to remove support for iCloud end-to-end encryption in the United Kingdom rather than give in to demands to add a backdoor for the government to access encrypted accounts. The UK's demand would have weakened Apple's encryption globally, but it was retracted last week following U.S. diplomatic pressure.

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Intel said Monday that converting $8.87 billion in federal chip subsidies into a 10% equity stake creates unprecedented complications and potential "adverse reactions" for a company deriving 76% of revenue internationally. The arrangement transforms Biden-era CHIPS Act grants into share purchases at $20.74 -- a discount to Friday's $24.80 close -- with the Department of Commerce receiving up to 433 million shares by Tuesday's expected closing. Foreign governments may impose additional regulations on Intel due to US government ownership, the company warned in securities filings, while the precedent could discourage other nations from offering grants if they expect similar equity conversions. China alone represents 29% of Intel's revenue. The deal also restricts Intel's strategic flexibility, requiring government votes align with board recommendations except on matters affecting federal interests.

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Living through extreme heat waves can accelerate your rate of aging, according to research published Monday. From a report: Scientists analyzed 15 years' worth of health data from nearly 25,000 adults in Taiwan and found that two years of exposure to heat waves could speed up a person's so-called biological aging by eight to 12 extra days. It may not sound like a lot, but this number builds over time, said Cui Guo, an assistant professor at the University of Hong Kong who led the study, which was published Monday in the journal Nature Climate Change. "This small number actually matters," she said. "This was a study of a two-year exposure, but we know heat waves have actually been occurring for decades." The research comes as human-induced climate change is making heat waves more intense and long-lasting. The West Coast of the United States is suffering from sweltering temperatures while Iran is experiencing searing heat. Record-breaking temperatures punished Europe, Japan and Korea earlier this month. France recently experienced its second heat wave of the summer, sparking a national debate over air-conditioning.

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Google will require identity verification for all Android app developers, including those distributing apps outside the Play Store, starting September 2026 in Brazil, Indonesia, Singapore, and Thailand before expanding globally through 2027. Developers must register through a new Android Developer Console beginning March 2026. The requirement applies to certified Android devices running Google Mobile Services. Google cited malware prevention as the primary motivation, noting sideloaded apps contain 50 times more malware than Play Store apps. Hobbyist and student developers will receive separate account types. Developer information submitted to Google will not be displayed to users.

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Security researchers have uncovered critical vulnerabilities in Perplexity's Comet browser that enable attackers to hijack user accounts and execute malicious code through the browser's AI summarization features. The flaws, discovered independently by Brave and Guardio Labs, exploit indirect prompt injection attacks that bypass traditional web security mechanisms when users request webpage summaries. Brave demonstrated account takeover through a malicious Reddit post that compromised Perplexity accounts when summarized. The vulnerability allows attackers to embed commands in webpage content that the browser's large language model executes with full user privileges across authenticated sessions. Guardio's testing found the browser would complete phishing transactions and prompt users for banking credentials without warning indicators. The paid browser, available to Perplexity Pro and Enterprise Pro subscribers since July, processes untrusted webpage content without distinguishing between legitimate instructions and attacker payloads.

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