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China's pharmaceutical industry has quietly evolved from a hub for generics and clinical trials into something more ambitious -- a genuine competitor in drug discovery that Western giants are now courting to fill gaps left by looming patent expirations worth over $300 billion by 2030. In the first half of 2025, nearly a third of global licensing agreements signed by big pharma involved Chinese firms, Economist reports, four times the share from 2021. Pfizer agreed in May to pay $1.25 billion to 3SBio for an experimental cancer drug, and GlaxoSmithKline followed in June with a deal valued at up to $12 billion with Hengrui. Chinese companies now run about a third of the world's clinical trials, up from 5% a decade ago.

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As Stranger Things releases the first four episodes of its final season today, nearly a decade after its July 2016 premiere, the Netflix series has come to represent something broader than its own popularity -- the embodiment of streaming television's algorithmic philosophy. When the show first appeared, streaming was still finding its footing. Netflix had been producing original series for only a few years, and services like Disney+, Apple TV and HBO Max did not yet exist. The question then was what form streaming originals would take: experimental fare like Sense8, nonlinear storytelling like the revived Arrested Development, or prestige dramas like House of Cards. The answer came from a popcorn horror thriller set in 1980s small-town Hawkins, Indiana. Matt and Ross Duffer built Stranger Things from vintage pop-culture parts -- Spielberg's coming-of-age sensibilities from E.T., Stephen King's horror and adolescent bonding, John Hughes' mean jocks and soulful goths, and references ranging from Kate Bush to The NeverEnding Story to casting Winona Ryder of Heathers and Beetlejuice fame. New York Times critic James Poniewozik calls the series "a human-made equivalent of the algorithm" -- the software engine that drives streaming's "if you liked that, you'll like this" recommendation philosophy. Netflix did not invent the idea of copying television success, but the algorithm automated it and made it part of the creative operating system. The show's structure also fits streaming's mechanics: binge-watching encouragement, irregular release schedules, and episodes that assume audiences have time (the last season finale ran two hours and 22 minutes). The story adds: It's why you see a menu of similar thumbnail recommendations once you finish streaming a favorite series, encouraging you not to discover but to replicate. But the spirit behind it also explains why so much original streaming TV feels like the creative product of an algorithm. Consider the recent Netflix drama "The Beast in Me," which pairs familiar prestige-TV stars (Claire Danes of "Homeland" and Matthew Rhys of "The Americans") in a grim, upscale thriller that vaguely recalls something you might have seen on early 2010s Showtime or FX. Creating the new by swallowing and regurgitating the old is also the signature move of generative A.I., which may be why that medium is so effective at creating works of burnished nostalgia. On Instagram and TikTok, accounts with names like "Maximal Nostalgia" serve up honeyed, uncanny images and videos that testify to how much better life was in a 1980s and 1990s that never existed.

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The European Parliament has passed a non-binding resolution urging an EU-wide minimum age of 16 to access social media, video-sharing platforms, and AI chatbots, with parental consent allowed for ages 13-16 and a hard ban for anyone under 13. "It also proposes additional measures, including a ban on addictive design features that keep children hooked to screens and manipulative advertising and gambling-like elements," reports Reuters. Furthermore, the draft "calls for the outright blocking of websites that don't follow EU rules and to address AI tools that can create fake or inappropriate content." The resolution "carries no legal weight" but reflects the growing concern on the issue of AI companions and algorithm-driven platforms even. "Any binding legislation would require formal proposals from the European Commission, followed by negotiations between EU member states and Parliament in a process that typically takes years to complete," notes the report.

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An anonymous reader quotes a report from the Conversation: The line between human and machine authorship is blurring, particularly as it's become increasingly difficult to tell whether something was written by a person or AI. Now, in what may seem like a tipping point, the digital marketing firm Graphite recently published a study showing that more than 50% of articles on the web are being generated by artificial intelligence. [...] It's important to clarify what's meant by "online content," the phrase used in the Graphite study, which analyzed over 65,000 randomly selected articles of at least 100 words on the web. These can include anything from peer-reviewed research to promotional copy for miracle supplements. A closer reading of the Graphite study shows that the AI-generated articles consist largely of general-interest writing: news updates, how-to guides, lifestyle posts, reviews and product explainers. The primary economic purpose of this content is to persuade or inform, not to express originality or creativity. Put differently, AI appears to be most useful when the writing in question is low-stakes and formulaic: the weekend-in-Rome listicle, the standard cover letter, the text produced to market a business. A whole industry of writers -- mostly freelance, including many translators -- has relied on precisely this kind of work, producing blog posts, how-to material, search engine optimization text and social media copy. The rapid adoption of large language models has already displaced many of the gigs that once sustained them. The dramatic loss of this work points toward another issue raised by the Graphite study: the question of authenticity, not only in identifying who or what produced a text, but also in understanding the value that humans attach to creative activity. How can you distinguish a human-written article from a machine-generated one? And does that ability even matter? Over time, that distinction is likely to grow less significant, particularly as more writing emerges from interactions between humans and AI... "If you set aside the more apocalyptic scenarios and assume that AI will continue to advance -- perhaps at a slower pace than in the recent past -- it's quite possible that thoughtful, original, human-generated writing will become even more valuable," writes author Francesco Agnellini, in closing. "Put another way: The work of writers, journalists and intellectuals will not become superfluous simply because much of the web is no longer written by humans."

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The Securities and Exchange Commission's possible plan to grant crypto companies relief from regulation to sell "tokenised" stocks risks harming investors, a group of stock exchanges said in a letter to the U.S. regulator this week. From a report: Several crypto companies plan to sell crypto tokens linked to listed equities to retail investors who want to get exposure to stocks without owning them directly. But to sell the products in the U.S., crypto companies which are not registered as broker-dealers would need the SEC to give them a no-action letter or an exemption. SEC Chair Paul Atkins has said the agency is working on crafting an "innovation exemption" from securities laws which would enable crypto players to experiment with new business models. The World Federation of Exchanges (WFE), a group whose members include the U.S. Nasdaq and Germany's Deutsche Boerse, said in a letter dated November 21 that an exemption could create market integrity risks and undermine investor protections. "The SEC should avoid granting exemptions to firms attempting to bypass regulatory principles that have safeguarded markets for decades," WFE CEO Nandini Sukumar told Reuters.

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An anonymous reader shares a report: The Pentagon concluded that Alibaba Group, Baidu and BYD should be added to a list of companies that aid the Chinese military, according to a letter to Congress sent roughly three weeks before Donald Trump and Xi Jinping agreed to a broad trade truce. Deputy Defense Secretary Stephen Feinberg informed lawmakers of the conclusion in the Oct. 7 letter, a copy of which was seen by Bloomberg News, to the heads of the House and Senate Armed Services Committees. It wasn't clear whether the companies have been formally included in the the Pentagon's so-called 1260H list, which carries no direct legal repercussions but serves as a major warning to US investors.

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OpenAI will need to raise at least $207 billion in new funding by 2030 to sustain operations while continuing to lose money, according to a new analysis from HSBC that models the company's cloud computing commitments against projected revenue. The bank's US software team updated its forecasts after OpenAI announced a $250 billion cloud compute rental deal with Microsoft in late October and a $38 billion deal with Amazon days later, bringing total contracted compute capacity to 36 gigawatts. HSBC projects cumulative rental costs of $792 billion through 2030. Revenue growth remains strong in the model -- the bank expects OpenAI to reach 3 billion users by decade's end, up from roughly 800 million today -- but costs rise in lockstep, meaning OpenAI will still be subsidizing users well into the next decade. If revenue growth disappoints and investors turn cautious, the company's best option might be walking away from some data center commitments.

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European manufacturers are facing a two-front assault from China that has German industry associations warning of deindustrialisation: on one side, artificially cheap Chinese goods are flooding into Europe, and on the other, Beijing has demonstrated its willingness to abruptly cut off access to critical inputs like rare earths and semiconductors. The alarm intensified in October when China added five rare earths to its export-licensing regime and then banned exports of computer chips made by Nexperia, a Dutch-headquartered but Chinese-owned chipmaker that supplies numerous European carmakers, according to The Economist. Several European firms warned of production stoppages, and some German companies put workers on leave without pay. Germany's trade deficit with China hit $76.52 billion last year and is expected to surge to around $100.87 billion this year, The Economist reported, driven by collapsing German exports and a rush of imports in categories like cars, chemicals, and machinery that were once German specialties. Chinese brands now account for 20% of Europe's hybrid market and 11% of electric vehicle sales. German cars command just 17% of the Chinese market, down from 27% in 2020. The rare earth controls were suspended for a year after the US and China struck a trade deal on October 30th, but the EU found itself a bystander to negotiations that directly affected its economy. Writing in the Financial Times, Robin Harding argues that China's explicit goal of self-sufficiency leaves Europe with few options. "There is nothing that China wants to import, nothing it does not believe it can make better and cheaper," he wrote, concluding that large-scale protectionism may be unavoidable if Europe wants to retain any industry at all.

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An anonymous reader shares a report: It is shocking but not surprising. Lightning crackles on Mars, scientists reported on Wednesday. What they observed, however, were not jagged, high-voltage bolts like those on Earth, arcing thousands of feet from cloud to ground. Rather, the phenomenon was more like the shock you feel when you scuff your feet on the carpet on a cold winter morning and then touch a metal doorknob. "This is like mini-lightning on Mars," Baptiste Chide, a scientist at the Research Institute in Astrophysics and Planetary Science in Toulouse, France, said of the centimeter-scale electrical discharges. Dr. Chide and his colleagues reported the findings in a paper published on Wednesday in the journal Nature. The electrical sparks, although not as dramatically violent as on Earth, could play an important role in chemical reactions in the Martian atmosphere.

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Dell has predicted PC sales will be flat next year, despite the potential of the AI PC and the slow replacement of Windows 10. From a report: "We have not completed the Windows 11 transition," COO Jeffrey Clarke said during Dell's Q3 earnings call on Tuesday. "In fact, if you were to look at it relative to the previous OS end of support, we are 10-12 points behind at that point with Windows 11 than we were the previous generation." Clarke said that means 500 million PCs can't run Windows 11, while the same number didn't need an upgrade to handle Microsoft's latest desktop OS. The COO therefore predicted the PC market will "flourish," but then defined the word as meaning "roughly flat" sales despite Dell chalking up mid-to high single digits PC sales growth over the last year.

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KDE's Plasma team has announced that KDE Plasma will drop X11 session support with Plasma 6.8:

The Plasma X11 session will be supported by KDE into early 2027.

We cannot provide a specific date, as we're exploring the possibility of shipping some extra bug-fix releases for Plasma 6.7. The exact timing of the last one will only be known when we get closer to its actual release, which we expect will be sometime in early 2027.

What if I still really need X11?

This is a perfect use case for long term support (LTS) distributions shipping older versions of Plasma. For example, AlmaLinux 9 includes the Plasma X11 session and will be supported until sometime in 2032.

See the blog post for information on running X11 applications (still supported), accessibility, gaming, and more.

Apple will retake its crown as the world's largest smartphone maker for the first time in more than a decade, lifted by the successful debut of a new iPhone series and a rush of consumers upgrading devices, according to Counterpoint Research. From a report: The iPhone 17 models introduced in September have been a hit both domestically in the US and in Apple's other critical market, China. They've enticed more people to upgrade, leading to double-digit year-over-year sales growth in both markets, according to the researchers. The US company also is benefiting from a cooling of US-China trade tensions and a depreciating dollar that has boosted purchases in emerging markets, they added. The growth will propel Apple past longtime rival Samsung this year, according to Counterpoint's figures. Shipments of the iPhone are set to grow at 10% in 2025, compared with 4.6% for Samsung.

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An anonymous reader shares a report: AI is not a core part of operations at most of the world's central banks and digital assets are off the table, according to a survey released on Wednesday by the Official Monetary and Financial Institutions Forum. The working group of 10 central banks from Europe, Africa, Latin America and Asia managing roughly $6.5 trillion in assets also found that the institutions that have delved deepest so far into AI are the most cautious about the risks. The primary concern is that AI-driven behaviour could "accelerate future crises," the survey showed. "AI helps us see more, but decisions must remain with people," one participant was quoted as saying in the group's report. More than 60% of respondents said that AI tools - which have sparked layoffs already at technology companies and retail and investment banks - are not yet supporting core operations.

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The roughly 500 fiber-optic cables lying on the ocean floor carry more than 95% of all internet data -- not satellites, as many might assume -- and they face growing threats from natural disasters, terrorists and nation-states capable of disrupting global communications by dragging anchors or deploying submarines against the infrastructure. The cables are protected by layers of copper, steel, and plastics, but they remain vulnerable at multiple points: earthquakes can disturb them on the seafloor, and the connections where cables meet land-based infrastructure present targets for bad actors. National actors including Russia, China and the US possess the capability to attack these cables. A bipartisan Senate bill co-sponsored by Democrat Jeanne Shaheen and Republican John Barrasso is under consideration. The legislation would require a report to Congress within six months on Chinese and Russian sabotage efforts, mandate sanctions against foreign parties responsible for attacks, and direct the US to provide more resources for cable protection and repair.

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Security updates have been issued by AlmaLinux (bind, binutils, delve and golang, expat, firefox, haproxy, kernel, libsoup3, libssh, libtiff, openssh, openssl, pam, podman, python-kdcproxy, shadow-utils, squid, thunderbird, vim, xorg-x11-server-Xwayland, and zziplib), Debian (cups-filters, libsdl2, linux-6.1, net-snmp, pdfminer, rails, and tryton-sao), Fedora (chromium, docker-buildkit, docker-buildx, and sudo-rs), Gentoo (librnp), Mageia (webkit2), SUSE (amazon-ssm-agent, buildah, curl, dpdk, fontforge-20251009, kernel, libIex-3_4-33, librnp0, python311, rclone, and sssd), and Ubuntu (linux, linux-aws, linux-aws-6.8, linux-ibm, linux-lowlatency, linux-lowlatency-hwe-6.8, linux-nvidia, linux-nvidia-6.8, linux-nvidia-lowlatency, linux-oracle, linux-aws-6.14, linux-oracle-6.14, linux-aws-fips, linux-fips, linux-gcp-fips, linux-realtime, linux-realtime-6.8, mupdf, openjdk-17, openjdk-8, and openjdk-lts).

Malaysia's Johor, one of Southeast Asia's fastest-growing data center hubs, has announced it will no longer approve applications for Tier 1 and Tier 2 data centers because of their enormous water consumption -- up to 50 million liters daily, or roughly 200 times what higher-tier facilities require. The Malaysian state has approved 51 data center projects as of November 2025. 17 centers are already operational, 11 are under construction and 23 received approval this year. The announcement follows concerns raised by a local politician who pointed to water supply disruptions in Georgia in the US after a data center began operations and protests in Uruguay over fears that data centers could affect farms.

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Texas has purchased $5 million worth of BlackRock's bitcoin ETF as an initial step toward creating the first state-level bitcoin reserve in the U.S. "[O]ther states having previously invested in such funds with public-employee retirement money," notes CoinDesk. "Michigan has been building such an investment, and Wisconsin sold its $350 million pension-fund stake in the BlackRock ETF in May. From the report: A few weeks ago, Texas moved past its deadline to "capture the industry's best practices so it can utilize these practices in the implementation and management" of its bitcoin BTC reserve, according to its formal request for information issued in September. Entities across the industry provided input on how it could set up and manage the stockpile conceived of in the Texas Strategic Bitcoin Reserve and Investment Act. Last week, the state comptroller's office moved to secure $5 million in BlackRock's iShares Bitcoin Trust (IBIT) as a placeholder, a spokesman for the Texas Comptroller of Public Accounts told CoinDesk on Tuesday. It's an opening move as the state continues to work toward a contract with a custodian, he said, which will take place after it develops its formal request for proposal.

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An anonymous reader quotes a report from the Guardian: Nearly a century ago, scientists proposed that a mysterious invisible substance they named dark matter clumped around galaxies and formed a cosmic web across the universe. What dark matter is made from, and whether it is even real, are still open questions, but according to a study, the first direct evidence of the substance may finally have been glimpsed. More work is needed to rule out less exotic explanations, but if true, the discovery would go down as a turning point in the decades-long search for the elusive substance that is said to make up 27% of the cosmos. "This could be a crucial breakthrough in unraveling the nature of dark matter," said Prof Tomonori Totani, an astrophysicist at the University of Tokyo, who said gamma rays emanating from the centre of the Milky Way appeared to bear the signature of the substance. [...] To search for potential dark matter signals, Totani analysed data from Nasa's Fermi Gamma-ray Space Telescope, which detects the most energetic photons in the electromagnetic spectrum. He spotted a pattern of gamma rays that appeared to match the shape of the dark matter halo that spreads out in a sphere from the heart of the galaxy. The signal "closely matches the properties of gamma-ray radiation predicted to be emitted by dark matter," Totani told the Guardian. Details are published in the Journal of Cosmology and Astroparticle Physics. If Totani has seen dark matter at work, the observations suggest it is made from elementary particles 500 times more massive than the proton. But far more work is needed to rule out other astrophysical processes and background emissions that could explain the signals. Totani said the "decisive factor" would be detecting gamma rays with the same spectrum from other regions of space, such as dwarf galaxies. According to Prof Justin Read, an astrophysicist at the University of Surrey, the lack of significant signals from such galaxies strongly argues against Totani having seen gamma rays emitted from dark matter particle annihilation. Prof Kinwah Wu, a theoretical astrophysicist at UCL, urged caution, saying: "I appreciate the author's hard work and dedication, but we need extraordinary evidence for an extraordinary claim," he said. "This analysis has not reached this status yet. It is a piece of work which serves as an encouragement for the workers in the field to keep on pressing."

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China launched an uncrewed Shenzhou 22 spacecraft to serve as an emergency lifeboat for three astronauts aboard the Tiangong space station after a docked return craft was found to have a cracked window likely caused by space debris. "A Long March 2F rocket fired its engines and lifted off with the Shenzhou 22 spacecraft, carrying cargo instead of a crew, at 11:11 pm EST Monday (04:11 UTC Tuesday)," reports Ars Technica. "The spacecraft docked with the Tiangong station nearly 250 miles (400 kilometers) above the Earth about three-and-a-half hours later." From the report: Chinese engineers worked fast to move up the launch of the Shenzhou 22, originally set to fly next year. On November 4, astronauts discovered one of the two crew ferry ships docked to the Tiangong station had a damaged window, likely from an impact with a small fragment of space junk. [...] Now, 20 days after the saga began, the Tiangong outpost again has a lifeboat for its long-term residents. Astronauts Zhang Lu, Fu Wei, and Zhang Hongzhang will return to Earth on the Shenzhou 22 spacecraft next year, soon after the arrival of their three replacements. The Tiangong astronauts will head outside the station on a spacewalk to inspect the damaged window on Shenzhou 20. Eventually, Shenzhou 20 will depart Tiangong and reenter the atmosphere with cargo. Assuming a smooth landing, Chinese engineers will have an opportunity to get a closer look at the damage on the ground to inform the design of future spacecraft. A preliminary assessment of the window indicates the crack is in the outermost layer of heat-insulating glass in Shenzhou 20's porthole window, according to Chinese state media. Engineers on the ground conducted simulations and wind tunnel ablation tests to determine whether the window might fail during reentry. "The results showed that the cracks would still propagate further," reported CCTV, China's government-run television network. "We held review meeting, and everyone agreed that ensuring the safe return of the astronauts was too risky with the glass damaged," Zhou said. While this crew is just one month into their planned six-month expedition, an emergency could force them to leave the station and return home at any time. Although remote, another collision with space junk, a major systems failure, or a medical emergency involving one of the astronauts could trigger an evacuation. That's why Chinese officials wanted to quickly launch Shenzhou 22 to give the crew a ticket home.The International Space Station follows the same policy, with SpaceX's Dragon spacecraft and Russian Soyuz ships serving as lifeboats until their crews' scheduled return to Earth.

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The UK is seeking to fast-track new atomic development to meet soaring energy demands driven by AI and electrification. According to a new report published by the government's Nuclear Regulatory Taskforce, excessive regulation has made Britain the most expensive place in the world to build nuclear projects. The report is calling for a sweeping overhaul to accelerate reactor construction -- everything from "streamlining regulation" to relaxing environmental and safety constraints. The Register reports: The document outlines 47 recommendations for the government, which come under five general areas: providing clearer leadership and direction for the nuclear sector; simplifying the regulatory approval process for atomic projects; reducing risk aversion; addressing incentives to delay progress; and working with the nuclear sector to speed delivery and boost innovation. Among the recommendations is that a Commission for Nuclear Regulation should be established, becoming a "unified decision maker" across all other regulators, planners, and approval bodies. The report also talks of reforming environmental and planning regimes to speed approvals, echoing the government's earlier decisions to streamline the planning process to make it easier for datacenter projects to get built. It recommends amending the cost cap for judicial reviews and limiting legal challenges to Nationally Strategic Infrastructure Projects (NSIPs), while indemnifying nuclear developers against any damages they might incur as a result of proceeding with their project while a judicial review is still being decided. Another recommendation that may be cause for concern is that the government should modify the Habitats Regulations to reduce costs. These are rules created to protect the most important and vulnerable natural sites and wildlife species across the UK. The report also states that radiation limits for workers are overly conservative and well below what could be appropriately considered "broadly acceptable," claiming that they are many times less than what the average person in the UK normally receives in a year.

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